Humidity is becoming more of a concern to building operators and owners. High indoor humidity leads to mold and mildew growth inside the building. The are several methods of controlling indoor humidity. The simplest (and most expensive) method is to connect a humidistat to an electric heater. When the humidity inside the building rises above the humidistat set point, the heater is turned on. The additional heat causes the air conditioning system to run longer and remove more moisture.
Without proper ventilation, carbon monoxide can be lethal at concentrations of 1000 ppm (0.1%). However, at several hundred ppm, carbon monoxide exposure induces headaches, fatigue, nausea, and vomiting. Carbon monoxide binds with hemoglobin in the blood, forming carboxyhemoglobin, reducing the blood's ability to transport oxygen. The primary health concerns associated with carbon monoxide exposure are its cardiovascular and neurobehavioral effects. Carbon monoxide can cause atherosclerosis (the hardening of arteries) and can also trigger heart attacks. Neurologically, carbon monoxide exposure reduces hand to eye coordination, vigilance, and continuous performance. It can also affect time discrimination.[15]
In the refrigeration cycle, heat is transported from a colder location to a hotter area. As heat would naturally flow in the opposite direction, work is required to achieve this. A refrigerator is an example of such a system, as it transports the heat out of the interior and into its environment. The refrigerant is used as the medium which absorbs and removes heat from the space to be cooled and subsequently ejects that heat elsewhere.
Air conditioning can also be provided by a process called free cooling which uses pumps to circulate a coolant (typically water or a glycol mix) from a cold source, which in turn acts as a heat sink for the energy that is removed from the cooled space. Common storage media are deep aquifers or a natural underground rock mass accessed via a cluster of small-diameter boreholes, equipped with heat exchanger. Some systems with small storage capacity are hybrid systems, using free cooling early in the cooling season, and later employing a heat pump to chill the circulation coming from the storage. The heat pump is added because the temperature of the storage gradually increases during the cooling season, thereby declining its effectiveness.
In 1820, English scientist and inventor Michael Faraday discovered that compressing and liquefying ammonia could chill air when the liquefied ammonia was allowed to evaporate. In 1842, Florida physician John Gorrie used compressor technology to create ice, which he used to cool air for his patients in his hospital in Apalachicola, Florida. He hoped to eventually use his ice-making machine to regulate the temperature of buildings. He even envisioned centralized air conditioning that could cool entire cities. Though his prototype leaked and performed irregularly, Gorrie was granted a patent in 1851 for his ice-making machine. Though his process improved the artificial production of ice, his hopes for its success vanished soon afterwards when his chief financial backer died and Gorrie did not get the money he needed to develop the machine. According to his biographer, Vivian M. Sherlock, he blamed the "Ice King", Frederic Tudor, for his failure, suspecting that Tudor had launched a smear campaign against his invention. Dr. Gorrie died impoverished in 1855, and the dream of commonplace air conditioning went away for 50 years.[citation needed]
HVAC is an important part of residential structures such as single family homes, apartment buildings, hotels and senior living facilities, medium to large industrial and office buildings such as skyscrapers and hospitals, on ships and submarines, and in marine environments, where safe and healthy building conditions are regulated with respect to temperature and humidity, using fresh air from outdoors.

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